Dr Mariano Mascarenhas
Medical Director
Specialties:
- Fertility Preservation
- PCOS
- Male infertility
- Donation
GMC reference number: 7478790
Dr Mariano Mascarenhas is the Medical Director at Care Fertility Leeds. His main clinical interest is fertility preservation. He also has a special interest in 3D ultrasound and in supporting women with complex medical conditions through their fertility pathway.
Training
- Studied medicine at Coimbatore Medical College, India, where he was the best outgoing student of his year
- Completed obstetrics and gynaecology training at JIPMER, India, and received a gold medal from the Prime Minister of India on completion
- Completed a fellowship in reproductive medicine at Christian Medical College, India, the first teaching hospital in India to offer an IVF service
- Holds Membership of the Royal College of Obstetricians and Gynaecologists (MRCOG)
- Holds the European Fellowship in Reproductive Medicine (EFRM) from the European Society of Human Reproduction and Embryology (ESHRE)
Career
Dr Mascarenhas spent six years as a clinical fellow at Leeds, during which he received the British Fertility Society Young Clinician award. He then moved to Glasgow, where he worked as a consultant. In Glasgow, he held the roles of Human Fertilisation and Embryology Authority (HFEA) person responsible and deputy medical director. He later returned to Care Fertility Leeds as a consultant in reproductive medicine, and now serves as Medical Director.
Specialities & Credentials
Mariano’s primary clinical interest is in fertility preservation and was part of a team which set up an online patient decision aid for women to navigate their fertility preservation options (www.cancerfertilityandme.org.uk). His special interests include the use of 3D ultrasound in the fertility treatment pathway and he was instrumental in setting up the 3D transvaginal ultrasound service at Leeds.
He has published over 30 papers in international peer-reviewed journals, written three book chapters, was the lead author on the British Fertility Society practice and policy paper on recurrent implantation failure and is a Cochrane author. He is the deputy to the practice and policy chair of the British Fertility Society.
He has a passion for teaching and an undergraduate project he supervised was awarded the best poster in the British Fertility Society conference in 2021.
Membership of Professional Bodies
Links to published works
- Kaur H, Chauhan A, Mascarenhas M. Does SARS Cov-2 infection affect the IVF outcome - A systematic review and meta-analysis. Eur J Obstet Gynecol Reprod Biol. 2023 Nov 22;292:147-157.
- Fleming R, Mascarenhas M, Roebuck F, Ambrose P, Noble C, Henderson A, Gibson N, Gaudoin M. FSH administration at 12-hour intervals for the first 2 days, combined with mandatory GnRH-agonist trigger and blastocyst vitrification in women (<80Kg) with high AMH levels, results in higher cumulative live birth rates and is safer. Hum Fertil (Camb). 2023 Jan 16:1-8.
- Jones GL, Moss RH, Darby F, Mahmoodi N, Phillips B, Hughes J, Vogt KS, Greenfield DM, Brauten-Smith G, Gath J, Campbell T, Stark D, Velikova G, Snowden JA, Baskind E, Mascerenhas M, Yeomanson D, Skull J, Lane S, Bekker HL, Anderson RA. Cancer, Fertility and Me: Developing and Testing a Novel Fertility Preservation Patient Decision Aid to Support Women at Risk of Losing Their Fertility Because of Cancer Treatment. Front Oncol. 2022 Jun 30;12:896939.
- Kamath V, Purna Chacko M, Kirubakaran R, Mascarenhas M, Kamath MS. Single nucleotide polymorphism array versus karyotype for prenatal diagnosis in fetuses with abnormal ultrasound: A systematic review and meta-analysis. Eur J Obstet Gynecol Reprod Biol. 2022 Apr;271:235-244.
- Sharpe A, Mascarenhas M, Balen A. Ethnic variation in the live birth rate and perinatal outcomes following frozen embryo transfer: an analysis of the HFEA database from 2000 to 2016. Hum Fertil (Camb). 2021 Apr 26:1-10.
- Mascarenhas M, Jeve Y, Polanski L, Sharpe A, Yasmin E, Bhandari HM. Management of recurrent implantation failure: British Fertility Society policy and practice guideline. Hum Fertil (Camb). 2021 Apr 5:1-25.
- Morris C, Rhymell R, Mascarenhas M, Bhandari HM. Ethnic and demographic variation in consenting for research in the context of fertility treatment. Human Fertility, January 2021
- Mascarenhas M, Kalampokas T, Sunkara SK, Kamath MS. Concordance between systematic reviews of randomized controlled trials in assisted reproduction: an overview, Human Reproduction Open, Volume 2020, Issue 4, 2020
- Mascarenhas M, Mehlawat H, Kirubakaran R, Bhandari HM, Choudhary M. Live birth and perinatal outcomes using cryopreserved oocytes: an analysis of the Human Fertilisation and Embryology Authority database from 2000 to 2016 using three clinical models, Human Reproduction, , deaa343, Epub December 2020
- Joseph T, Mascarenhas M, Karuppusami R, Karthikeyan M, Kunjummen AT, Kamath MS. Antioxidant pretreatment for male partner before ART for male factor subfertility: a randomized controlled trial, Human Reproduction Open, Volume 2020, Issue 4, 2020, hoaa050
- Arakkal D, Mascarenhas M, Mangalaraj AM, Karthikeyan M, Prasad JH, Kunjummen AT, Kamath MS. Comparison of Low Cost Versus Conventional Assisted Reproductive Technology Treatment: A Prospective Micro Costing Study. Fertility & Reproduction 2020 02:03, 102-107
- Kamath MS, Mascarenhas M, Kirubakaran R, Bhattacharya S. Number of embryos for transfer following in vitro fertilisation or intra-cytoplasmic sperm injection. Cochrane Database Syst Rev. 2020 Aug 21;8
- , June 2020, Pages 53-58
- Kamath MS, Mascarenhas M, Franik S, Liu E, Sunkara SK. Clinical adjuncts in in vitro fertilization: a growing list. Fertil Steril. 2019 Dec;112(6):978-986.
- Mascarenhas M, Balen AH. Could ethnicity have a different effect on fresh and frozen embryo transfer outcomes: a retrospective study. Reprod Biomed Online. 2019 Nov;39(5):764-769
- Richardson A, Mascarenhas M, Balen AH. Is a woman's chronological age or 'ovarian age' more important in determining perinatal outcome after assisted reproductive treatment? Hum Fertil (Camb). 2019 Apr 30:1-7.
- Mascarenhas M, Kulkarni M, Balen AH. Can the ethnic differences in IVF cycle outcome be influenced by the impact of BMI? Hum Fertil (Camb). 2019 Jan 14:1-7.
- Mascarenhas, M. , Oliver, J. and Bhandari, H. M. (2018), Routes to parenthood for women with Turner syndrome. Obstet Gynecol.
- Mascarenhas M, Fox SJ, Thompson K, Balen AH. Cumulative live birth rates and perinatal outcomes with the use of time-lapse imaging incubators for embryo culture: a retrospective cohort study of 1882 ART cycles. BJOG. 2019 Jan;126(2):280-286.
- Kamath MS, Kirubakaran R, Mascarenhas M, Sunkara SK. Perinatal outcomes after
stimulated versus natural cycle IVF: a systematic review and meta-analysis.
Reprod Biomed Online. 2018 Jan;36(1):94-101. - Mascarenhas M, Sunkara SK, Antonisamy B, Kamath MS. Higher risk of preterm birth and low birth weight following oocyte donation: A systematic review and meta-analysis. Eur J Obstet Gynecol Reprod Biol. 2017 Sep 19;218:60-67.
- Kamath MS, Antonisamy B, Mascarenhas M, Sunkara SK. High-risk of preterm birth and low birth weight after oocyte donation IVF: analysis of 133,785 live births. Reprod Biomed Online. 2017 Sep;35(3):318-324.
- Mascarenhas M, Rawnsley V, Balen A. Iron overload directly affecting the
ovaries in a patient with Diamond-Blackfan anaemia: a case report. Hum Fertil
(Camb). 2017 Jun 23:1-5 - Kamath MS, Mascarenhas M, Kirubakaran R, Nair R, Kulkarni A. Use of embryo
culture supernatant to improve clinical outcomes in assisted reproductive
technology: a systematic review and meta-analysis. Hum Fertil (Camb). 2017 Apr
26:1-8. - Kamath MS, Chittawar PB, Kirubakaran R, Mascarenhas M. Use of
granulocyte-colony stimulating factor in assisted reproductive technology: A
systematic review and meta-analysis. Eur J Obstet Gynecol Reprod Biol. 2017
Jul;214:16-24. doi: 10.1016/j.ejogrb.2017.04.022. Epub 2017 Apr 13. - Mascarenhas M, Balen AH. The high responder: a review of pathophysiology and outcomes during IVF treatment. Hum Fertil. 2017 Feb 28;0(0):1–13.
- Mascarenhas M, Thomas S, Kamath MS, Ramalingam R, Kongari AM, Yuvarani S, Srivastava VM, George K. Prevalence of chromosomal abnormalities and Y chromosome microdeletion among men with severe semen abnormalities and its correlation with successful sperm retrieval. J Hum Reprod Sci 2016;9:187-93
- Mascarenhas M, Gnanaprabha K. Monozygotic Pregnancies Following Assisted Reproductive Technology: A Review. EMJ Repro Health. 2016;2[1]:79-85
- Mascarenhas M, Kamath MS, Chandy A, Kunjummen AT. Progesterone/Estradiol Ratio as a Predictor in the ART Cycles with Premature Progesterone Elevation on the Day of hCG Trigger. J Reprod Infertil. 2015;16(3):155-161
- Kamath MS, Mascarenhas M, B K, Vasani NN, Joshi A, K M, George K. Uterine flushing with supernatant embryo culture medium in vitrified warmed blastocyst transfer cycles: a randomized controlled trial. J Assist Reprod Genet. 2015 Feb;32(2):225-31.
- Mascarenhas M, Kamath MS, Muthukumar K, Mangalaraj AM, Chandy A, Aleyamma T. Obstetric outcomes of monochorionic pregnancies conceived following assisted reproductive technology: A retrospective study. J Hum Reprod Sci. 2014 Apr;7(2):119-24.
- Mascarenhas M, Habeebullah S, Sridhar MG. Revisiting the role of first
trimester homocysteine as an index of maternal and fetal outcome. J Pregnancy.
2014;2014:123024. doi: 10.1155/2014/123024. Epub 2014 May 5. - Sagili H, Pramya N, Prabhu K, Mascarenhas M, Reddi Rani P. Are teenage pregnancies at high risk? A comparison study in a developing country. Arch Gynecol Obstet. 2012 Mar;285(3):573-7.
- Dasari P, Maurya DK, Mascarenhas M. Uterine artery pseudoaneurysm: a rare cause of secondary postpartum haemorrhage following caesarean section. BMJ Case Rep. 2011 Mar 25;2011.
Book chapters:
- Targeting infertility in PCOS: unfolding "Ariadne's thread" Mascarenhas M, Balen AH
- Woodward and Mehta. Female infertility: core principles and clinical management. Chapter 11. Implantation - Mascarenhas M, Kamath MS, Sunkara SK
- Bricker, Robinson and Thilaganathan. Management of Multiple Pregnancy. Assisted conception and multiple pregnancy: strategies to reduce rates. Mascarenhas M, Balen AH
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